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Invitrogen™ CDC7 Polyclonal Antibody
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Catalog No. PIPA5109501
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100 μL
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PIPA5109501 100 μL
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Catalog No. PIPA5109501 Supplier Invitrogen™ Supplier No. PA5109501
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EGSVGLSVQR SVFGERNFNI HSSISHESPA VKLMKQSKTV DVLSRKLATK KKAISTKVMN SAVMRKTASS CPASLTCDCY ATDKVCSICL SRRQQVAPRA GTPGFRAPEV LTKCPNQTTA IDMWSAGVIF LSLLSGRYPF YKASDDLTAL AQIMTIRGSR ETIQAAKTFG KSILCSKEVP AQDLRKLCER LRGMDSSTPK LTSDIQGHAS HQPAISEKTD HKASCLVQTP PGQYSGNSFK KGDSNSCEHC FDEYNTNLEG WNEVPDEAYD LLDKLLDLNP ASRITAEEAL LHPFFKDMSL.

CDC7 is a cell division cycle 7 homolog protein that is critical for the G1/S transition and is also essential for initiation of DNA replication as cell division occurs. CDC7 is expressed in many normal tissues, but the overexpression of CDC7 may be associated with neoplastic transformation for some tumors and transformed cell lines. CDC7/DBF4 kinase promotes S phase by alleviating an inhibitory activity in Mcm4 that evolved to integrate several protein kinase. CDC7 encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDC7
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.42 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CDC7
Gene Accession No. O00311
Gene Alias AI597260; Cdc7; CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1; Cdc7 Kinase; Cdc7l1; CDC7-like 1; CDC7-related kinase; cell division cycle 7; cell division cycle 7 (S. cerevisiae); cell division cycle 7 homolog; cell division cycle 7-like 1; cell division cycle 7-like protein 1; cell division cycle 7-related protein kinase; HsCDC7; Hsk1; huCDC7; MGC117361; MGC126237; MGC126238; MGC91067; muCdc7
Gene Symbols CDC7
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 275-574 of human CDC7 (NP_001127892.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8317
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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