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Invitrogen™ Cdc7 Recombinant Rabbit Monoclonal Antibody (SY21-01)
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Catalog No. PIMA532081
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PIMA532081 100 μL
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Catalog No. PIMA532081 Supplier Invitrogen™ Supplier No. MA532081
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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

CDC7 is a cell division cycle 7 homolog protein that is critical for the G1/S transition and is also essential for initiation of DNA replication as cell division occurs. CDC7 is expressed in many normal tissues, but the overexpression of CDC7 may be associated with neoplastic transformation for some tumors and transformed cell lines. CDC7/DBF4 kinase promotes S phase by alleviating an inhibitory activity in Mcm4 that evolved to integrate several protein kinase. CDC7 encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cdc7
Applications Flow Cytometry, Western Blot
Classification Recombinant Monoclonal
Clone SY21-01
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene CDC7
Gene Accession No. O00311, Q9Z0H0
Gene Alias AI597260; Cdc7; CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1; Cdc7 Kinase; Cdc7l1; CDC7-like 1; CDC7-related kinase; cell division cycle 7; cell division cycle 7 (S. cerevisiae); cell division cycle 7 homolog; cell division cycle 7-like 1; cell division cycle 7-like protein 1; cell division cycle 7-related protein kinase; HsCDC7; Hsk1; huCDC7; MGC117361; MGC126237; MGC126238; MGC91067; muCdc7
Gene Symbols CDC7
Host Species Rabbit
Immunogen Synthetic peptide within Human CDC7 Kinase aa 1-50.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12545, 360908, 8317
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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