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Invitrogen™ Cdc73 Polyclonal Antibody
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Catalog No. PIPA517158
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100 μL
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PIPA517158 100 μL
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Catalog No. PIPA517158 Supplier Invitrogen™ Supplier No. PA517158
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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

Cdc73 is a tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. Cdc73 is part of the PAF1 complex, a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9. PAF1 was first purified from yeast in association with RNA polymerase II and is believed to function in transcription elongation. The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription. In addition to coordinating events during transcription (initiation, promoter clearance, and elongation), hPAF also coordinates events in RNA quality control. Cdc73 may also be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cdc73
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene CDC73
Gene Accession No. Q4V8C8, Q6P1J9, Q8JZM7
Gene Alias 8430414L16Rik; BC027756; C130030P16Rik; C1orf28; C81219; Cdc73; cell division cycle 73; cell division cycle 73 Paf1/RNA polymerase II complex component-like protein; cell division cycle 73, Paf1/RNA polymerase II complex component; cell division cycle 73, Paf1/RNA polymerase II complex component, homolog; cell division cycle protein 73 homolog; FIHP; HPTJT; HRPT1; HRPT2; hyperparathyroidism 2 (with jaw tumor); hyperparathyroidism 2 homolog; hyperparathyroidism 2 protein; Hyperparathyroidism 2 protein homolog; HYX; Paf1/RNA polymerase II complex component; parafibromin; Vcell division cycle 73, Paf1/RNA polymerase II complex component, homolog
Gene Symbols CDC73
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues surrounding Ala264 of human CDC73.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 214498, 304832, 79577
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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