Invitrogen™ CDCA7L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531761

Catalog No. PIPA531761

Description

Recommended positive controls: U87-MG. Predicted reactivity: Mouse (86%), Rat (85%), Rhesus Monkey (99%), Chimpanzee (98%), Bovine (88%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Cell division cycle-associated 7-like protein (or RAM2) is a transcription factor which plays a role in transcriptional regulation and apoptotic signaling pathways. It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to promoter. It also plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. It may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

Specifications

• Antigen: CDCA7L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDCA7L
• Gene Alias: BC006933; CDCA7L; cell division cycle associated 7 like; cell division cycle associated 7-like; cell division cycle-associated 7-like protein; HR1; JPO2; Protein JPO2; R1; RAM2; transcription factor RAM2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55536
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96GN5
• Gene Symbols: CDCA7L
• Immunogen: Recombinant fragment corresponding to a region within amino acids 184 and 397 of Human CDCA7L.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov