Invitrogen™ CDH10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5144705

Catalog No. FEPA5144705

Description

Immunogen sequence: SGTTTVNITL TDVNDNPPRF PQNTIHLRVL ESSPVGTAIG SVKATDADTG KNAEVEYRII DGDGTDMFDI VTEKDTQEGI ITVKKPLDYE SRRLYTLKVE AENTHVDPRF YYLGPFKDTT IVKISIEDVD EPPVFSRSSY LFEVH Antigen sequence identity: Mouse 97%; Rat 97%.

CDH10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.

Specifications

• Antigen: CDH10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cdh10
• Gene Alias: A830016G23Rik; C030003B10Rik; C030011H18Rik; Cadherin; cadherin 10; cadherin 10 type 2; cadherin 10, type 2 (T2-cadherin); cadherin-10; Cdh10; T2-cadherin
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1008
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Isotype: IgG

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y6N8
• Gene Symbols: Cdh10
• Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 250-394. Recombinant protein control fragment (Product #RP-109975).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Format: Liquid