Invitrogen™ CDH12 Monoclonal Antibody (01), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA543513

Catalog No. PIMA543513

Description

Specificity: Human Cadherin-12/CDH12

CDH12 is a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.

Specifications

• Antigen: CDH12
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P55289
• Gene Symbols: CDH12
• Immunogen: Recombinant Human Cadherin-12/CDH12 Protein.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA
• Clone: 01
• Conjugate: Unconjugated
• Gene: CDH12
• Gene Alias: Brain cadherin; brain-cadherin; Br-cadherin; Cadherin; cadherin 12; cadherin 12, type 2 (N-cadherin 2); cadherin, neural type, 2; cadherin-12; CDH12; CDHB; N-cadherin 2; neural type cadherin 2; neuronal cadherin 2; RGD1566350
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1010
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid