Invitrogen™ CDH18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553162

Catalog No. PIPA553162

Description

Immunogen sequence: DNPPRFPQKH YQLYVPESAQ VGSAVGKIKA NDADTGSNAD MTYSIINGDG MGIFSISTDK ETREGILSLK KPLNYEKKKS YTLNIEGANT HLDFRFSHLG PFKDATMLKI IVGDVDEPPL FSMPSYLMEV YENAKIGTVV GTVLAQDPD Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.

This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Specifications

• Antigen: CDH18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDH18
• Gene Alias: B230220E17Rik; Cadherin; Cadherin 14; cadherin 18; cadherin 18, type 2; Cadherin14; cadherin-14; Cadherin18; Cadherin-18; cadherin-like 24; CDH14; Cdh14l; CDH18; CDH24; ey-cadherin
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1016
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q13634
• Gene Symbols: CDH18
• Immunogen: Recombinant protein corresponding to Human CDH18. Recombinant protein control fragment (Product #RP-90592).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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