Invitrogen™ CDH20 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553309

Catalog No. PIPA553309

Description

Immunogen sequence: PFQDTTTVHI SVEDVDEPPV FEPGFYFVEV PEDVAIGTTI QIISAKDPDV TNNSIRYSID RSSDPGRFFY VDITTGALMT ARPLDREEFS WHNITVLAME MNNPSQVGSV PVTIKV Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.

Specifications

• Antigen: CDH20
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDH20
• Gene Alias: Cad20; Cadherin; cadherin 20; cadherin 20, type 2; cadherin 7; cadherin-20; Cadherin-7; Cdh20; Cdh7; CDH7L3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 28316
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9HBT6
• Gene Symbols: CDH20
• Immunogen: Recombinant protein corresponding to Human CDH20. Recombinant protein control fragment (Product #RP-90036).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov