Invitrogen™ CDH4 Monoclonal Antibody (OTI4F5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526686

Catalog No. PIMA526686

Description

CDH4 Monoclonal Antibody for Western Blot, IHC (P)

CDH4 is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: CDH4
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P55283
• Gene Symbols: Cdh4
• Immunogen: Human recombinant protein fragment corresponding to amino acids 170-428 of CDH4 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4F5
• Conjugate: Unconjugated
• Gene: Cdh4
• Gene Alias: AW120700; CAD4; Cadherin; cadherin 4; cadherin 4 type 1 R-cadherin (retinal); cadherin 4, type 1, preproprotein; cadherin 4, type 1, R-cadherin (retinal); cadherin-4; Cdh4; Cdh4l; Rcad; R-CAD; R-Cadh; R-cadherin; retina cadherin; retinal cadherin
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1002
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid