CDH4 Mouse anti-Human, Clone: OTI4D9, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF804818
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCOCDH4 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.
|Human recombit protein fragment corresponding to amino acids 170-428 of human CDH4 produced in E.coli.|
|PBS with 8% trehalose and no preservative; pH 7.3|
|CAD4, R-CAD, RCAD|
|-20° C, Avoid Freeze/Thaw Cycles|
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