CDH4 Mouse anti-Human, Clone: OTI4F5, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF804735

Catalog No. 50-166-7107

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

CDH4 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.

Specifications

• Antigen: CDH4
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CDH4
• Gene Alias: CAD4, R-CAD, RCAD
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1002
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4F5
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P55283
• Gene Symbols: CDH4
• Immunogen: Human recombit protein fragment corresponding to amino acids 170-428 of human CDH4 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1