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Invitrogen™ CDH4 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA578376
Description
Predicted Reactivity: Human (100%), Chicken (91%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CDH4 is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.
Specifications
CDH4 | |
Polyclonal | |
Unconjugated | |
Cdh4 | |
AW120700; CAD4; Cadherin; cadherin 4; cadherin 4 type 1 R-cadherin (retinal); cadherin 4, type 1, preproprotein; cadherin 4, type 1, R-cadherin (retinal); cadherin-4; Cdh4; Cdh4l; Rcad; R-CAD; R-Cadh; R-cadherin; retina cadherin; retinal cadherin | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
1002, 12561 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin) | |
1 mg/mL | |
PBS with 20% glycerol and 0.01% thimerosal; pH 7 | |
P39038, P55283 | |
Cdh4 | |
Recombinant protein encompassing a sequence within the center region of human R-cadherin. The exact sequence is proprietary. | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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