CDH5 Monoclonal Antibody (OTI1E1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA804747

Catalog No. 50-168-0383

Description

VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer. VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.

Specifications

• Antigen: CDH5
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P33151
• Gene Symbols: CDH5
• Immunogen: Human recombit protein fragment corresponding to amino acids 48-333 of human CDH5 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1E1
• Conjugate: Unconjugated
• Gene: CDH5
• Gene Alias: 7B4, CD144
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1003
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid