CDH5 Mouse anti-Human, Rat, Clone:3D5C7, Abnova™

Mouse monoclonal antibody raised against recombinant human CDH5.

Supplier:  Abnova Corporation MAB17796

Catalog No. 89-334-481

Description

This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq]

Specifications

• Antigen: CDH5
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000)
  Flow Cytometry (1:200-1:400)
  Immunocytochemistry
  Immunohistochemistry
  Western Blot (1:500-1:2000)
  The optimal working dilution should be determined by the end user.
• Gene: CDH5
• Host Species: Mouse
• Quantity: 100 μg
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 3D5C7
• Description: cadherin 5, type 2 (vascular endothelium)
• Formulation: In PBS (0.05% sodium azide)
• Gene Alias: 7B4, CD144, FLJ17376
• Immunogen: Recombinant protein corresponding to amino acids 29-223 of human CDH5 from E. coli.
• Gene ID (Entrez): 1003
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid