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CDHF14 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983105
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100 μL
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50-198-3105 100 μL
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Catalog No. 50-198-3105 Supplier Bioss Supplier No. BS13721R
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Rabbit Polyclonal Antibody

FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). FAT4 undergo the first proteolytic cleavage by Furin and are predicted to undergo the second cleavage by secretase to release intracellular domain (ICD). FAT4 directly interacts with MPDZ/MUPP1 to recruit membrane associated guanylate kinase MPP5/PALS1. FAT4 is involved in the maintenance of PCP and inhibition of cell proliferation.

Specifications

Antigen CDHF14
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene FAT4
Gene Accession No. Q6V0I7
Gene Alias 6030410K14Rik; 9430004M15; Cadherin family member 14; cadherin-related family member 11; CDHF14; CDHR11; FAT atypical cadherin 4; FAT tumor suppressor homolog 4; FAT tumor suppressor homolog 4 (Drosophila); Fat4; FATJ; FAT-J; Fat-like cadherin protein FAT-J; hFat4; HKLLS2; Nbla00548; Protocadherin Fat 4; putative protein product of Nbla00548; VMLDS2
Gene Symbols FAT4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human CDHF14.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79633
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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