CDK11 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No.	Quantity
50-155-7354	100 μL

Catalog No. 50-155-7354 Supplier Bethyl Laboratories, Inc Supplier No. A300310A

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse

The PITSLRE beta1 protein, a distantly related member of the Cdk family of protein kinases, induces apoptosis after low levels of ectopic expression. Apoptosis, or programmed cell death, is similarly induced by ectopic expression of an amino terminal deletion mutant retaining the catalytic and carboxyterminal domains of PITSLRE beta1, but not by other mutants lacking Histone H1 kinase activity or by other Cdk family members. The terminology for the ten isoforms of the PITSLRE subfamily of proteins is based on the conserved PSTAIRE box region of Cdc2 p34. Depending on which of the PITSLRE genes produce the protein, the cDNA and protein are designated alpha, beta or gamma (i.e., PITSLRE A gene, alpha; PITSLRE B gene, beta and PITSLRE C gene, gamma). Some of the isoforms such as PITSLRE alpha1 (T cells) and PITSLRE beta1 (B cells and brain), are expressed in specific cell types, while others are expressed ubiquitously.

Specifications

• Antigen: CDK11
• Applications: Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/ml
• Conjugate: Unconjugated
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene: CDK11A
• Gene Accession No.: Q9UQ88
• Gene Alias: CDC2L2, CDC2L3, CDK11, CDK11 p110, CDK11 p46, CDK11 p58, CDK11A, CDK8 like cyclin dependent kinase, Cell division cycle 2 like 2 (PITSLRE proteins), Cell division cycle 2 like protein kinase 2, Cell division cycle 2-like protein kinase 2, Cell division protein kinase 11A, Cyclin dependent kinase (CDC2 like) 11, Cyclin-dependent kinase 11A, Death preventing kinase, Galactosyltransferase associated protein kinase p58/GTA, Galactosyltransferase-associated protein kinase p58/GTA
• Gene Symbols: CDK11A
• Host Species: Rabbit
• Immunogen: Between 50 and 100
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 728642
• Target Species: Human
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG