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Invitrogen™ Human CDK14 (PFTK1)/cyclin Y, GST Tag Recombinant Protein

Catalog No. PV6382
Encompass_Preferred
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Quantity:
1 mg
10 μg
100 μg

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Recombinant human full-length CDK14 and Cyclin Y (2-end) were co-expressed by baculovirus in Sf9 insect cells using N-terminal GST tags. , Validated in LanthaScreen™ Kinase Binding Assay, Protocols available for simple use and optimized performance, Multiple pack sizes available for convenient use Protein Form: Recombinant The gene accession number for the two subunits (CDK14[PFTK1] and Cyclin y) are NP_036527.1 and NP_659449.3.

CDK14 (PFTK1)/cyclin Y is a member of the CDC2-related protein kinase family which is expressed primarily in the postnatal and adult nervous system. CDK14 is expressed at high levels in brain, pancreas, kidney, heart, testis, and ovary. CDK14 amino acid residue ser119 is required for its interaction with all four 14-3-3 isoforms, while ser120 may contribute slightly to CDK14 binding. CDK14 acts as a cyclin-dependent kinase that regulates cell cycle progression and cell proliferation. Overexpression of CDK14 predicts resistance to chemotherapy in patients with esophageal squamous cell carcinoma.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O94921
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50 mM tris HCl with 0.1 mM EDTA, 0.1 mM PMSF, 0.25 mM DTT, 10 mM glutathione, 150 mM NaCl, 25% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 5218
Molecular Weight (g/mol) 77.0-65.5 kDa
Name Human CDK14 (PFTK1)/cyclin Y, GST Tag
Quantity 10 μg
Gene Alias Cdk14; Cell division protein kinase 14; cyclin dependent kinase 14; cyclin-dependent kinase 14; hPFTAIRE1; Kiaa0834; mKIAA0834; PFTAIRE protein kinase 1; PFTAIRE1; Pftk1; Serine/threonine-protein kinase PFTAIRE-1
Common Name PFTK1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence CDK14: 1-469; Cyclin Y: 2-341
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Expression System Baculovirus
Form Liquid
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