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Invitrogen™ CDK2 Monoclonal Antibody (10-D7)
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Catalog No. PIMA532903
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100 μL
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PIMA532903 100 μL
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Catalog No. PIMA532903 Supplier Invitrogen™ Supplier No. MA532903
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Description

Mouse Monoclonal Antibody

CDK2 Monoclonal Antibody for ICC/IF, Western Blot

CDK2/cyclinO is a member of the cyclin dependent protein kinase family complexed to CyclinO. CyclinO was used as a specific protein isoform name for the UNG gene which is localized exclusively in the nucleus. In addition, CyclinO was reported to shows significant uracil-DNA glycosylase activity. CDK2/cyclinO protein levels increase during G1 phase and the protein is turned over during the course of cell cycle. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDK2
Applications Western Blot, Immunocytochemistry, Western Blot
Classification Monoclonal
Clone 10-D7
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% Glycerol, 0.2% BSA and 0.05% sodium azide; pH 7.4
Gene CDK2
Gene Accession No. P24941, P97377, Q63699
Gene Alias A630093N05Rik; CDC28; CDC2A; cdc2-related protein kinase; CDK1; CDK2; CDKN2; Cell division protein kinase 2; cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; cyclin-dependent kinase 2; EC 2.7.11.22; EC 2.7.11.23; kinase Cdc2; MPF; p33 protein kinase; p33(CDK2); p33CDK2; p34 protein kinase
Gene Symbols CDK2
Host Species Mouse
Immunogen Synthetic peptide within Human CDK2 aa 249-298.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1017, 12566, 362817
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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