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CDK2 Monoclonal Antibody (OTI5A10), TrueMAB™, OriGene
SDP

Catalog No. 501674072
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30 μL
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50-167-4072 100 μL
50-254-1115 30 μL
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Catalog No. 50-167-4072 Supplier OriGene Supplier No. TA503104
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Description

Mouse Monoclonal Antibody

p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as does cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.

Specifications

Antigen CDK2
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Monoclonal
Clone OTI5A10
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene CDK2
Gene Accession No. P24941
Gene Alias CDKN2, p33(CDK2)
Gene Symbols CDK2
Host Species Mouse
Immunogen Full length human recombit protein of human CDK2 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1017
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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