CDK2 Monoclonal Antibody (OTI6H2), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA502936

Catalog No. 50-167-3932

Description

p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as does cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.

Specifications

• Antigen: CDK2
• Classification: Monoclonal
• Concentration: 0.17 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P24941
• Gene Symbols: CDK2
• Immunogen: Full length human recombit protein of human CDK2 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI6H2
• Conjugate: Unconjugated
• Gene: CDK2
• Gene Alias: CDKN2, p33(CDK2)
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1017
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid