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CDK2 Mouse anti-Human, Clone: OTI1C4, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA502807

Catalog No. 50-167-3820



Description

Description

p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as does cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.
Specifications

Specifications

CDK2
Monoclonal
0.65 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P24941
CDKN2, p33(CDK2)
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1017
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI1C4
Unconjugated
CDK2
Liquid
CDK2
Full length human recombit protein of human CDK2 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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