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Invitrogen™ CDK2AP1 Polyclonal Antibody
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Catalog No. PIPA599197
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100 μL
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PIPA599197 100 μL
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Catalog No. PIPA599197 Supplier Invitrogen™ Supplier No. PA599197
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CDKA1 / DOC1.

The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDK2AP1
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CDK2AP1
Gene Accession No. O14519, O35207
Gene Alias Apc10; CDK2 (cyclin-dependent kinase 2)-associated protein 1; Cdk2ap1; CDK2-associated protein 1; CDKAP1; cyclin dependent kinase 2 associated protein 1; cyclin-dependent kinase 2 associated protein 1; cyclin-dependent kinase 2-associated protein 1; Deleted in oral cancer 1; Deleted in oral cancer-1; Doc1; doc-1; DORC1; p12; p12DOC-1; Putative oral cancer suppressor; ST19
Gene Symbols CDK2AP1
Host Species Rabbit
Immunogen A synthesized peptide derived from human CDK2AP1(Accession O14519), corresponding to amino acid residues H10-A30.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13445, 8099
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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