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Invitrogen™ CDK5 Monoclonal Antibody (4E4)
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Catalog No. PIMA517053
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100 μL
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Catalog No. Quantity
PIMA517053 100 μL
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Catalog No. PIMA517053 Supplier Invitrogen™ Supplier No. MA517053
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Description

Mouse Monoclonal Antibody

MA5-17053 targets CDK5 in indirect ELISA, FACS, ICC, IHC, IF and WB applications and shows reactivity with Human, Non-human primate, and Rat samples. The MA5-17053 immunogen is purified recombinant fragment of human CDK5 expressed in E. Coli. MA5-17053 detects CDK5 which has a predicted molecular weight of approximately 35kDa.

CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDK5
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 4E4
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene CDK5
Gene Accession No. P49615, Q00535, Q03114
Gene Alias AW048668; Cdk5; CDK5 activator 1; CDK5-SV; CDKN5; Cell division protein kinase 5; CR6 protein kinase; Crk6; cyclin dependent kinase 5; cyclin-dependent kinase 5; cyclin-dependent-like kinase 5; LIS7; protein kinase CDK5 splicing; PSSALRE; Serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit
Gene Symbols CDK5
Host Species Mouse
Immunogen Purified recombinant fragment of human CDK5 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1020, 12568, 140908
Target Species Human, Mouse, Rat, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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