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Invitrogen™ CDK5 Recombinant Rabbit Monoclonal Antibody (7C8T10)
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Catalog No. PIMA535214
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100 μL
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PIMA535214 100 μL
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Catalog No. PIMA535214 Supplier Invitrogen™ Supplier No. MA535214
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: AELANAGRPL FPGNDVDDQL KRIFRLLGTP TEEQWPSMTK LPDYKPYPMY PATTSLVNVV PKLNATGRDL LQNLLKCNPV QRISAEEALQ HPYFSDFCPP.

CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDK5
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 7C8T10
Concentration 0.64 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CDK5
Gene Accession No. P49615, Q00535, Q03114
Gene Alias AW048668; Cdk5; CDK5 activator 1; CDK5-SV; CDKN5; Cell division protein kinase 5; CR6 protein kinase; Crk6; cyclin dependent kinase 5; cyclin-dependent kinase 5; cyclin-dependent-like kinase 5; LIS7; protein kinase CDK5 splicing; PSSALRE; Serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit
Gene Symbols CDK5
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 193-292 of human Cdk5 (Q00535).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1020, 12568, 140908
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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