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CDK5 Mouse anti-Canine, Human, Clone: OTI2H6, liquid, TrueMAB™
SDP

Catalog No. 501671531
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50-167-1531 100 μL
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Catalog No. 50-167-1531 Supplier OriGene Supplier No. TA500397
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Description

Mouse Monoclonal Antibody

Cyclin-dependent kinase-5 (CDK5) is a member of the cyclin-dependent kinase family of serine/threonine kinases. Its mRNA and protein are expressed in the kidneys, testes, and ovaries. And Its activity has been detected almost exclusively in brain extracts. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity; however, Cdk5 is not activated bycyclins. Instead, Cdk5 activity requires association with one of two brain-specific regulatory subunits, called p35 and p39. These two activators regulate the spatial and temporal expression of active Cdk5, restricting its activity primarily to post-mitotic neurons.

Specifications

Antigen CDK5
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Classification Monoclonal
Clone OTI2H6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene CDK5
Gene Accession No. Q00535
Gene Alias LIS7, PSSALRE
Gene Symbols CDK5
Host Species Mouse
Immunogen Full length human recombit protein of human CDK5 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1020, 475537
Target Species Canine, Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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