CDK5 Mouse anti-Canine, Human, Clone: OTI2H6, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA500397

Catalog No. 50-167-1531

Description

Cyclin-dependent kinase-5 (CDK5) is a member of the cyclin-dependent kinase family of serine/threonine kinases. Its mRNA and protein are expressed in the kidneys, testes, and ovaries. And Its activity has been detected almost exclusively in brain extracts. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity; however, Cdk5 is not activated bycyclins. Instead, Cdk5 activity requires association with one of two brain-specific regulatory subunits, called p35 and p39. These two activators regulate the spatial and temporal expression of active Cdk5, restricting its activity primarily to post-mitotic neurons.

Specifications

• Antigen: CDK5
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q00535
• Gene Symbols: CDK5
• Immunogen: Full length human recombit protein of human CDK5 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Canine, Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI2H6
• Conjugate: Unconjugated
• Gene: CDK5
• Gene Alias: LIS7, PSSALRE
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1020, 475537
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid