Invitrogen™ CDK6 Recombinant Rabbit Monoclonal Antibody (0O6X7)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535046

Catalog No. PIMA535046

Description

Immunogen sequence: QLGKILDVIG LPGEEDWPRD VALPRQAFHS KSAQPIEKFV TDIDELGKDL LLKCLTFNPA KRISAYSALS HPYFQDLERC KENLDSHLPP SQNTSELNTA.

CDK6 functions as a cell-cycle initiator protein. This protein is coexpressed and copurified with CyclinD1. They are critical regulators of cell cycle progression. The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression. CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles. Mutations in the gene results in microcephaly 12, primary, autosomal recessive (MCPH12).

Specifications

• Antigen: CDK6
• Classification: Recombinant Monoclonal
• Concentration: 0.25 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q00534
• Gene Symbols: CDK6
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 227-326 of human CDK6 (Q00534).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 0O6X7
• Conjugate: Unconjugated
• Gene: CDK6
• Gene Alias: 5830411I20; AI504062; CDK6; CDKN6; Cell division protein kinase 6; CR2 protein kinase; Crk2; cyclin dependent kinase 6; cyclin-dependent kinase 6; MCPH12; MGC59692; PLSTIRE; Serine/threonine-protein kinase PLSTIRE
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1021, 114483
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid