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Cdk6 Monoclonal Antibody (K6.83 (DCS-83)), Invitrogen™
Mouse Monoclonal Antibody
Supplier: Thermo Scientific MA513333
Description
MA5-13333 targets Cdk6 in ICC/IF, immunohistochemistry (frozen), immunohistochemistry (paraffin), immunoprecipitation, and Western blot applications and shows reactivity with Human, mouse, and Rat samples. The MA5-13333 immunogen is purified recombinant cdk6 protein.
CDK6 functions as a cell-cycle initiator protein. This protein is coexpressed and copurified with CyclinD1. They are critical regulators of cell cycle progression. The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression. CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles. Mutations in the gene results in microcephaly 12, primary, autosomal recessive (MCPH12).
Specifications
Cdk6 | |
Monoclonal | |
0.2 mg/mL | |
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 | |
Q00534, Q64261 | |
CDK6 | |
Purified recombinant cdk6 protein | |
500 μL | |
Primary | |
Human, Mouse, Rat | |
Liquid |
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
K6.83 (DCS-83) | |
Unconjugated | |
CDK6 | |
5830411I20; AI504062; CDK6; CDKN6; Cell division protein kinase 6; CR2 protein kinase; Crk2; cyclin dependent kinase 6; cyclin-dependent kinase 6; MCPH12; MGC59692; PLSTIRE; Serine/threonine-protein kinase PLSTIRE | |
Mouse | |
Protein G | |
RUO | |
1021, 114483, 12571 | |
4° C | |
IgG1 |
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