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CDK6 Monoclonal Antibody (K6.90 (DCS-90)), Invitrogen™

Catalog No. PIMA513338
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500 μL
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Catalog No. Quantity
PIMA513338 500 μL
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Catalog No. PIMA513338 Supplier Thermo Scientific Supplier No. MA513338
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Description

Mouse Monoclonal Antibody

MA5-13338 targets Cdk6 in IF, IHC (F), IP, and WB applications and shows reactivity with Human, mouse, and Rat samples. The MA5-13338 immunogen is purified recombinant cdk6 protein.

CDK6 functions as a cell-cycle initiator protein. This protein is coexpressed and copurified with CyclinD1. They are critical regulators of cell cycle progression. The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression. CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles. Mutations in the gene results in microcephaly 12, primary, autosomal recessive (MCPH12).
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDK6
Applications Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone K6.90 (DCS-90)
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene CDK6
Gene Accession No. Q00534, Q64261
Gene Alias 5830411I20; AI504062; CDK6; CDKN6; Cell division protein kinase 6; CR2 protein kinase; Crk2; cyclin dependent kinase 6; cyclin-dependent kinase 6; MCPH12; MGC59692; PLSTIRE; Serine/threonine-protein kinase PLSTIRE
Gene Symbols CDK6
Host Species Mouse
Immunogen Purified recombinant cdk6 protein
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1021, 114483, 12571
Target Species Human, Mouse, Rat
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1
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