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Invitrogen™ CDK6 Recombinant Rabbit Monoclonal Antibody (SD20-50)
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA532357
Description
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
CDK6 functions as a cell-cycle initiator protein. This protein is coexpressed and copurified with CyclinD1. They are critical regulators of cell cycle progression. The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression. CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles. Mutations in the gene results in microcephaly 12, primary, autosomal recessive (MCPH12).
Specifications
CDK6 | |
Recombinant Monoclonal | |
1 mg/mL | |
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4 | |
Q00534 | |
CDK6 | |
Synthetic peptide within Human Cdk6 aa 277-326. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot | |
SD20-50 | |
Unconjugated | |
CDK6 | |
5830411I20; AI504062; CDK6; CDKN6; Cell division protein kinase 6; CR2 protein kinase; Crk2; cyclin dependent kinase 6; cyclin-dependent kinase 6; MCPH12; MGC59692; PLSTIRE; Serine/threonine-protein kinase PLSTIRE | |
Rabbit | |
Protein A | |
RUO | |
1021 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
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