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Invitrogen™ CDKL2 Monoclonal Antibody (OTI12C2)
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Catalog No. PIMA526746
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100 μL
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PIMA526746 100 μL
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Catalog No. PIMA526746 Supplier Invitrogen™ Supplier No. MA526746
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Description

Mouse Monoclonal Antibody

CDKL2 Monoclonal Antibody for Western Blot, IHC (P)

The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis, kidney, brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However, unlike other MAP kinases, the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDKL2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI12C2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CDKL2
Gene Accession No. Q92772
Gene Alias 5330436L21Rik; AI505225; CDC2-related kinase; Cdkl2; cyclin dependent kinase like 2; cyclin-dependent kinase-like 2; cyclin-dependent kinase-like 2 (CDC2-related kinase); Kkiamre; Kkm; P56; p56 KKIAMRE protein kinase; protein kinase p56 KKIAMRE; serine/threonine protein kinase KKIAMRE; serine/threonine-protein kinase KKIAMRE; testicular tissue protein Li 35
Gene Symbols CDKL2
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 291-493 of CDKL2 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8999
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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