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Invitrogen™ CDKL5 Polyclonal Antibody
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Catalog No. PIPA5103286
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100 μL
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PIPA5103286 100 μL
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Catalog No. PIPA5103286 Supplier Invitrogen™ Supplier No. PA5103286
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CDKL5.

CDKL5 serine/threonine kinase (STK9) is associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome and Rett syndrome (RTT). CDKL5 can control nuclear speckle morphology by regulating the phosphorylation state of splicing regulatory proteins, and may be involved indirectly in pre-mRNA processing by controlling splicing factor dynamics. The mutations in CDKL5 are major cause of infantile spasms and early epileptic seizures in female patients, and of a later intractable seizure disorder.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDKL5
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CDKL5
Gene Accession No. O76039, Q3UTQ8
Gene Alias BC038161; Cdkl5; CFAP247; cyclin dependent kinase 5 transcript; cyclin dependent kinase like 5; cyclin-dependent kinase-like 5; EIEE2; ISSX; RP1-245G19.3; serine/threonine kinase 9; serine/threonine-protein kinase 9; STK9
Gene Symbols CDKL5
Host Species Rabbit
Immunogen A synthesized peptide derived from human CDKL5(Accession O76039), corresponding to amino acid residues E666-Y716.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 382253, 6792
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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