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Invitrogen™ CDKN2B (Isoform 2) Polyclonal Antibody
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Catalog No. PIPA5142832
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100 μg
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Catalog No. Quantity
PIPA5142832 100 μg
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Catalog No. PIPA5142832 Supplier Invitrogen™ Supplier No. PA5142832
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Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize isoform 2 (NP_511042.1) only. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008].
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDKN2B (Isoform 2)
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene CDKN2B
Gene Accession No. P42772
Gene Symbols CDKN2B
Host Species Goat
Immunogen Peptide with sequence C-RQGARERGARP.
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1030
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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