CDKN2B Mouse anti-Human, Clone: OTI8H4, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF505208

Catalog No. 50-166-3468

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The four known 15-to 19 kDa INK4 proteins (p15INK4b, p16INK4a, p18INK4c andp19INK4d) bind and inhibit CDK4 and CDK6 but not other CDKs, including cyclin E-Cdk2, cyclin A-Cdk2 and cyclin B-Cdk1. Like the three D-type cyclins, the INK4 genes are expressed in distinct tissue-specific patterns, suggesting that they are not strictly redundant. 5 p18INK4c is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S-phase.

Specifications

• Antigen: CDKN2B
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CDKN2B
• Gene Alias: CDK4I, INK4B, MTS2, P15, TP15, p15INK4b
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1030
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI8H4
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P42772
• Gene Symbols: CDKN2B
• Immunogen: Full length human recombit protein of human CDKN2B produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1