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Invitrogen™ CDKN2B Polyclonal Antibody
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Catalog No. PIPA5116445
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PIPA5116445 100 μL
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Catalog No. PIPA5116445 Supplier Invitrogen™ Supplier No. PA5116445
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Description

Rabbit Polyclonal Antibody

Positive controls: Hela, SiHa, rat kidney tissue, human esophagus cancer tissue, human small intestine tissue, mouse liver tissue.

The four known 15-to 19 kDa INK4 proteins (p15INK4b, p16INK4a, p18INK4c andp19INK4d) bind and inhibit CDK4 and CDK6 but not other CDKs, including cyclin E-Cdk2, cyclin A-Cdk2 and cyclin B-Cdk1. Like the three D-type cyclins, the INK4 genes are expressed in distinct tissue-specific patterns, suggesting that they are not strictly redundant. 5 p18INK4c is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S-phase.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDKN2B
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.2% BSA and 0.05% sodium azide; pH 7.4
Gene CDKN2B
Gene Accession No. P42772, P55271, P55272
Gene Alias AV083695; CDK inhibitory protein; CDK4B inhibitor; CDK4I; Cdkn2b; cyclin dependent kinase inhibitor 2B; Cyclin dependent kinase inhibitor 2B (p15, inhibits CDK4); cyclin-dependent kinase 4 inhibitor B; cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4); cyclin-dependent kinase inhibitor p15; cyclin-dependent kinase inhibitor p15INK4b; cyclin-dependent kinase inhibitor protein; cyclin-dependent kinases 4 and 6 binding protein; Ink4; INK4B; MTS2; MTS-2; Multiple tumor suppressor 2; p14_CDK inhibitor; p14_INK4B; p14-INK4b; P15; p15 CDK inhibitor; p15(INK4b); p15_INK4B; p15INK4b; p15-INK4b; TP15
Gene Symbols CDKN2B
Host Species Rabbit
Immunogen Recombinant protein within Human p15 INK4b aa 1-138.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1030, 12579, 25164
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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