CDKN2C Monoclonal Antibody (OTI5G1), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-8745	100 μL

Catalog No. 50-167-8745 Supplier OriGene Supplier No. TA801230

Description

Mouse Monoclonal Antibody

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.

Specifications

• Antigen: CDKN2C
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI5G1
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: CDKN2C
• Gene Accession No.: P42773
• Gene Alias: INK4C, p18, p18-INK4C
• Gene Symbols: CDKN2C
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human CDKN2C produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1031
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a