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Invitrogen™ CDKN2C Polyclonal Antibody
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Catalog No. PIPA582660
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100 μL
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PIPA582660 100 μL
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Catalog No. PIPA582660 Supplier Invitrogen™ Supplier No. PA582660
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LQTLLEFQAD VNIEDNEGNL PLHLAAKEGH LRVVEFLVKH TASNVGHRNH KGDTACDLAR LYGRNEVVSL MQANG Highest antigen sequence indentity to the following orthologs: Rat - 88%, Mouse - 88%.

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDKN2C
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CDKN2C
Gene Accession No. P42773
Gene Alias C77269; CDK6 inhibitor p18; Cdkn2c; CDKN6; cyclin dependent kinase inhibitor 2C; cyclin-dependent inhibitor; cyclin-dependent kinase 4 inhibitor C; Cyclin-dependent kinase 6 inhibitor; cyclin-dependent kinase 6 inhibitor p18; cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4); INK4c; p18; p18INK4c; p18-INK4c; p18-INK6
Gene Symbols CDKN2C
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CDKN2C. Recombinant protein control fragment (Product #RP-92522).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1031
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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