Invitrogen™ CDKN3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566218

Catalog No. PIPA566218

Description

Immunogen sequence: TISPEQAIDSL RDLRGSGAIQ TIKQYNYLHE FRDKLAAHLS SRDSQSRSVS R Highest antigen sequence identity to the following orthologs - mouse 90%, rat 90%.

The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: CDKN3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDKN3
• Gene Alias: 2410006H10Rik; CDI1; CDK2-associated dual specificity phosphatase; CDK2-associated dual-specificity phosphatase; CDK2-associated dual-specificity phosphatase {ECO:0000250; Cdk-associated protein phosphatase; Cdkn3; cdkn3 {ECO:0000312; CIP2; cyclin dependent kinase inhibitor 3; cyclin-dependent kinase inhibitor; cyclin-dependent kinase inhibitor 3; cyclin-dependent kinase inhibitor 3 {ECO:0000250; cyclin-dependent kinase interacting protein 2; cyclin-dependent kinase interactor 1; Cyclin-dependent kinase-interacting protein 2; EMBL:AAI67026.1, ECO:0000312; KAP; KAP1; kinase associated phosphatase; kinase-associated phosphatase; kinase-associated phosphatase {ECO:0000250; RGD:1307781}; UniProtKB:Q16667}
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1033
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q16667
• Gene Symbols: CDKN3
• Immunogen: Recombinant Human CDKN3. Recombinant protein control fragment (Product #RP-106900).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG