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Tocris Bioscience™ CDN 1163
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Catalog No. 586910
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Catalog No. Quantity
58-691-0 10 mg
58-695-0 50 mg
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Catalog No. 58-691-0 Supplier Tocris Bioscience™ Supplier No. 5869/10
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Description

SERCA2 allosteric activator

CDN 1163 is a SERCA2 allosteric activator. Increases Ca2+-ATPase activity and Ca2+ uptake by ER microsomes from obese mice. Rescues HEK cells from ER stress-induced cell death. Reduces fasting glucose levels and adipose tissue weight, and increases energy expenditure in ob/ob mice. Also improves glucose tolerance and reverses hepatic steatosis in ob/ob mice. Neuroprotective and improves memory and cognition in a mouse Alzheimer's disease model. Orally bioavailable.

Specifications

Chemical Name or Material 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide
CAS 892711-75-0
Quantity 10 mg
Target Ca2+-ATPase Activators
Molecular Formula C20H20N2O2
Formula Weight 320.38
Purity >98%
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