CDX2 Monoclonal Antibody (OTI5A1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA802665

Catalog No. 50-167-9339

Description

CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.

Specifications

• Antigen: CDX2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q99626
• Gene Symbols: CDX2
• Immunogen: Full length human recombit protein of human CDX2 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: OTI5A1
• Conjugate: Unconjugated
• Gene: CDX2
• Gene Alias: CDX-3, CDX2/AS, CDX3
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1045
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid