Invitrogen™ CDY1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590567

Catalog No. PIPA590567

Description

Immunogen sequence: EKQKKLTWTT TSRIFSNNAR RRTSRSTKAN YSKNSPKTPV TDKHHRSKNR KLFAASKNVR RKAASILSDT KNMEIINSTI ETLAPDSPFD HKTVSGFQKL EKLDPIAADQ QDTVVFKVTE GKLLRDPLSR PGAEQTGIQN KTQIHPLMSQ MSGSVTASMA TGSATRKGIV VLIDPLAANG TTDMHTSVPR VKGGQRNITD DSRDQPFIKK MHFTIRLTES ASTYRDIVVK KEDGFTQIVL STRSTEKNAL NTEVIKEIVN A; Positive Samples: Mouse testis, Rat testis; Cellular Location: Nucleus.

CDY1 containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined.

Specifications

• Antigen: CDY1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: CDY; CDY1; CDY1A; CDY1B; chromodomain protein, Y chromosome, 1; chromodomain protein, Y-linked, 1; testis-specific chromodomain protein on Y; testis-specific chromodomain protein Y 1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-320 of human CDY1B (NP_0010038951).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.46 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG