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CEACAM1/CEACAM5 Monoclonal Antibody (4/3/17), Invitrogen™

Catalog No. 01670180
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100 μg
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Catalog No. Quantity
01-670-180 100 μg
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Catalog No. 01-670-180 Supplier Thermo Scientific Supplier No. MA117767

Item Discontinued This product is either new or inactive, and cannot be ordered online.This item has been discontinued by the supplier. Please to view product availability in your area.

Mouse Monoclonal Antibody

This antibody recognizes native human CEACAM1, 5 protein expressed in transfected mammalian cells.

Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker CEACAM1 expression is down-regulated in many tumors indicating a tumor-suppressive function. The anti-tumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CEACAM1/CEACAM5
Applications ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
Classification Monoclonal
Clone 4/3/17
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.2
Gene CEACAM1
Gene Accession No. P06731, P13688
Gene Alias antigen CD66; BGP; BGP1; BGP-1; BGPI; Biliary glycoprotein 1; Carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen related cell adhesion molecule 5; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); carcinoembryonic antigen-related cell adhesion molecule 5; CD66a; CD66a antigen; CD66e; CEA; CEACAM1; CEACAM5; Meconium antigen 100; pan CEACAM; sCD66e; soluble CD66e
Gene Symbols CEACAM1, CEACAM5
Host Species Mouse
Immunogen Extracted protein of CEACAM5
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1048, 634
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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