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Invitrogen™ CEACAM1/CEACAM5 Recombinant Rabbit Monoclonal Antibody (BLR032F)
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Catalog No. PIMA544259
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100 μL
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PIMA544259 100 μL
PIMA544260 10 μL
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Catalog No. PIMA544259 Supplier Invitrogen™ Supplier No. MA544259
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Description

Rabbit Recombinant Monoclonal Antibody

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker CEACAM1 expression is down-regulated in many tumors indicating a tumor-suppressive function. The anti-tumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CEACAM1/CEACAM5
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone BLR032F
Concentration 50 μg/mL
Conjugate Unconjugated
Formulation BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
Gene CEACAM1
Gene Accession No. P06731, P13688
Gene Alias antigen CD66; BGP; BGP1; BGP-1; BGPI; Biliary glycoprotein 1; Carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen related cell adhesion molecule 5; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); carcinoembryonic antigen-related cell adhesion molecule 5; CD66a; CD66a antigen; CD66e; CEA; CEACAM1; CEACAM5; Meconium antigen 100; pan CEACAM; sCD66e; soluble CD66e
Gene Symbols CEACAM1, CEACAM5
Host Species Rabbit
Immunogen Recombinant protein representing the extracellular domain of human CEACAM1 (residues 35-433).
Purification Method Purified
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1048, 634
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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