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Invitrogen™ CEACAM1 Polyclonal Antibody
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Catalog No. PIPA5117502
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100 μg
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PIPA5117502 100 μg
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Catalog No. PIPA5117502 Supplier Invitrogen™ Supplier No. PA5117502
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Description

Rabbit Polyclonal Antibody

This antibody has been tested in direct-ELISA.

CEACAM1 is a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of only two has been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CEACAM1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene CEACAM1
Gene Accession No. P13688
Gene Alias antigen CD66; ATP-dependent taurocolate-carrier protein; bb-1; BGP; BGP1; BGP-1; BGPI; BGPR; Biliary glycoprotein 1; biliary glycoprotein D; bone gamma-carboxyglutamic acid (Gla) protein; carcinoembryonic antigen 1; carcinoembryonic antigen 7; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); Cc1; C-CAM; C-CAM 105; Ccam1; CD66a; CD66a antigen; Cea1; Cea-1; Cea7; Cea-7; CEACAM1; CEA-related cell adhesion molecule 1; CEA-related cell adhesion molecule 1 (bone gamma-carboxyglutamic acid (Gla) protein) (osteocalcin); Cell-CAM 105; ecto-ATPase; GP110; hepatitis virus (MHV-4) susceptibility; hepatitis virus receptor; Hv2; Hv-2; mCEA1; Mhv-1; MHVR; MHV-R; MHVR1; mmCGM1; mmCGM1a; mmCGM2; murine hepatitis virus receptor; osteocalcin; pp120; pp120/ecto-ATPase
Gene Symbols CEACAM1
Host Species Rabbit
Immunogen Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 1 protein (35-428aa).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 634
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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