CEACAM1 Recombinant Rabbit Monoclonal Antibody (BLR032F), Bethyl Laboratories

Rabbit Recombit Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-157-2658	Bethyl Laboratories, Inc A700032T	10 μL
50-157-2657	Bethyl Laboratories, Inc A700032	100 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For ICC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections. For IHC, epitope retrieval with citrate buffer pH 6.0 is recommende

CEACAM1 is a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregcy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of only two has been determined.

Specifications

• Antigen: CEACAM1
• Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: P13688
• Gene ID (Entrez): 634
• Immunogen: recombit protein representing the extracellular domain of human CEACAM1.
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: CEACAM1

• Clone: BLR032F
• Classification: Recombinant Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2
• Gene Alias: BGP, BGP1, BGPI, CD66a antigen, antigen CD66, carcinoembryonic antigen-related cell adhesion molecule 1
• Gene Symbols: CEACAM1
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody