CEACAM6 Recombinant Rabbit Monoclonal Antibody (408), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Supplier:  Thermo Scientific MA529144

Catalog No. PIMA529144

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombit rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombit rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human CEACAM6/CD66c.

CEA-related cell adhesion molecule 6 (CEACAM6, NCA) belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein with a MW of 90kDa which is strongly expressed on epithelial cells of the fetal and adult gastrointestinal tract, epithelia of glandular tissues, squamous epithelial cell of the tongue, esophagus and cervix as well as on granulocytes. CEACAM6 expression is upregulated in many adenocarcinomas and leukemias. Like all members of the CEA family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constant-like A and B domain.

Specifications

• Antigen: CEACAM6
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Gene: CEACAM6
• Gene Alias: CD66c, CEAL, NCA, carcinoembryonic antigen-related cell adhesion molecule 6, non-specific crossreacting antigen, normal cross-reacting antigen
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4680
• Content And Storage: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: 408
• Formulation: PBS with no preservative
• Gene Accession No.: P40199
• Gene Symbols: CEACAM6
• Immunogen: Recombit Human CD66c protein
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG