Invitrogen™ CELA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5122103

Catalog No. PIPA5122103

Description

CELA1 Polyclonal Antibody for Western Blot, IHC (P)

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 (ELA1) expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A.Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A.

Specifications

• Antigen: CELA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CELA1
• Gene Alias: 1810009A17Rik; 1810062B19Rik; Cela1; chymotrypsin like elastase 1; chymotrypsin like elastase family member 1; chymotrypsin-like elastase family member 1; chymotrypsin-like elastase family, member 1; ELA1; Ela-1; ELAI1; elastase 1; elastase 1, pancreatic; elastase I; Elastase-1; ELS1; pancreatic elastase 1; pancreatic elastase I; pancreatic preproelastase I; PC-TsF; preproelastase I; RATELAI1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 109901, 24331, 396766
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: P00772, P00773, Q91X79
• Gene Symbols: CELA1
• Immunogen: Recombinant protein Pancreatic Elastase 1. The antigen corresponds to amino acid range 44-259 of the target protein.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Pig, Rat
• Product Type: Antibody
• Isotype: IgG