Invitrogen™ CELSR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533422

Catalog No. PIPA533422

Description

Percent identity with other species by BLAST analysis: Human, Bovine, Dog, Panda (100%) Elephant, Rabbit (95%) Gibbon, Rat (90%) Mouse (85%).

The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.

Specifications

• Antigen: CELSR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CELSR2
• Gene Alias: ADGRC2; adhesion G protein-coupled receptor C2; cadherin EGF LAG seven-pas G-type receptor 2; cadherin EGF LAG seven-pass G-type receptor 2; Cadherin family member 10; cadherin, EGF LAG seven-pass G-type receptor 2; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); CDHF10; Celsr2; EGFL2; EGF-like protein 2; EGF-like-domain, multiple 2; epidermal growth factor-like 2; epidermal growth factor-like protein 2; flamingo; Flamingo homolog; flamingo homolog 3; Flamingo1; flamingo-like protein celsr2; FLJ34118; FLJ42737; FLJ45143; FLJ45845; KIAA0279; MEGF3; mfmi1; mKIAA0279; Multiple EGF-like domains protein 3; multiple epidermal growth factor-like domains 3; multiple epidermal growth factor-like domains protein 3; seven-pass transmembrane cadherin
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1952, 479916, 538194
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9HCU4
• Gene Symbols: CELSR2
• Immunogen: Synthetic 20 amino acid peptide from N-terminal extracellular domain of human CELSR2 / EGFL2.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Canine, Bovine
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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