Invitrogen™ CELSR3 Polyclonal Antibody

Catalog No.	Quantity
PIPA533424	50 μg

Catalog No. PIPA533424

Supplier: Invitrogen™ PA533424

Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Bovine, Panda (100%).

CELSR3 is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.

Specifications

• Antigen: CELSR3
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% sodium azide
• Gene: CELSR3
• Gene Accession No.: Q9NYQ7
• Gene Alias: Adgrc3; adhesion G protein-coupled receptor C3; anchor protein; cadherin EGF LAG seven-pass G-type receptor 3; Cadherin family member 11; cadherin, EGF LAG seven-pass G-type receptor 3; cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila); CDHF11; Celsr3; EGFL1; EGF-like protein 1; EGF-like-domain, multiple 1; Epidermal growth factor-like protein 1; flamingo; flamingo homolog 1; FMI1; hFmi1; KIAA0812; Megf2; Megf3; mKIAA0812; multiple EGF-like domains protein 2; multiple epidermal growth factor-like domains 2; multiple epidermal growth factor-like domains protein 2; RESDA1
• Gene Symbols: CELSR3
• Host Species: Rabbit
• Immunogen: Synthetic 20 amino acid peptide from N-terminal extracellular domain of human CELSR3.
• Purification Method: Antigen Affinity Chromatography
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1951, 523793
• Target Species: Human, Bovine
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov