Cenexin-1Rabbit anti-Chimpanzee, Human, Rhesus Monkey, Polyclonal, Rockland™

Rabbit Polyclonal Antibody

Supplier:  Rockland Immunochemicals 600401A46

Catalog No. 50-199-1934

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This antibody is specific for human Cenexin-1 protein. A BLAST analysis was used to suggest cross-reactivity with Cenexin-1 from human, chimpanzee and macaque based on 100% homology with the immunizing sequence. Cross-reactivity with Cenexin-1from other sources has not been determined.

Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.

Specifications

• Antigen: Cenexin-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ODF2
• Gene Alias: 84 kDa outer dense fiber protein; AI848335; cancer/testis antigen 134; Cenexin; cenexin 1; CT134; KKT4; MMTEST29; ODF2; ODF2/1; ODF2/2; Odf84; outer dense fiber of sperm tail 2; outer dense fiber of sperm tails 2; Outer dense fiber of sperm tails protein 2; outer dense fiber of sperm tails, 84-kD; Outer dense fiber protein 2; RP11-187B3.1; sperm outer dense fiber major protein 2; sperm tail structural protein; testis tissue sperm-binding protein Li 51e; testis-specific autoantigen
• Host Species: Rabbit
• Regulatory Status: RUO
• Gene ID (Entrez): 464769, 4957, 717505
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Accession No.: Q5BJF6
• Gene Symbols: ODF2
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Chimpanzee, Human, Rhesus Monkey
• Product Type: Antibody