Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
CENP-B Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
$156.65 - $620.58
Specifications
| Antigen | CENP-B |
|---|---|
| Concentration | Lot-Specific |
| Applications | Immunoprecipitation, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-199-3304
|
Active Motif
61288 |
10 μL |
Each for $156.65
|
|
|||||
|
50-199-3303
|
Active Motif
61287 |
100 μL |
Each for $620.58
|
|
|||||
Description
CENPB is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes and is considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.Specifications
| CENP-B | |
| Immunoprecipitation, Western Blot | |
| Unconjugated | |
| Rabbit | |
| Human | |
| P07199 | |
| 1059 | |
| This CENP-B antibody was raised against a recombinant protein corresponding to the C-terminal region of human CENP-B. | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| CENPB |
| Lot-Specific | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 30% glycerol and 0.035% sodium azide; pH 7.5 | |
| Cenpb; Cenp-b; CENP-B protein; centromere autoantigen B; Centromere protein B; centromere protein B, 80kDa; Major centromere autoantigen B | |
| CENPB | |
| IgG | |
| Antigen affinity chromatography | |
| Antibody |
Spot an opportunity for improvement?Share a Content Correction
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title